新蒲京娱乐场官网8555cc(澳门)股份有限公司

　　职 称：讲 师

　　学院系所：新蒲京娱乐场官网8555cc，动物及发育生物学系

　　学科领域：生殖生物学

　　联系电话：18222429896

　　电子邮件：qdguian@sina.com

　　通讯地址：山东省青岛市城阳区长城路700号新蒲京娱乐场官网8555cc/生物楼B601房间

 

　　个人简介：

　　黄桂安，博士，讲师。

　　天津市131创新型人才培养工程第三层次

　　教学工作：

1.       新蒲京娱乐场官网app下载：动物学。　　 ​​

　　科研方向：

1.        生殖相关关键基因功能研究
2. 　　环境有害物质生殖毒理研究

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　　科研项目：

1. 　　国家自然科学基金：Tet1/Tet2敲除影响小鼠精原干细胞自我更新和多能性及其分子机制，31900589，24万
2. 　　国家重点研发计划：线粒体遗传疾病治疗的辅助生殖新技术研究，2018YFC1003000，课题4“基因编辑技术在线粒体遗传病治疗的可行性探索”，210万  

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　　科研奖励：

　　无 

　　发明专利：

　　无

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　　​代表性论文：

1. Huang Guian#; Liu Linlin#; Wang Huasong#; Gou Mo; Gong Peng; Tian Chenglei; Deng Wei; Yang Jiao; Zhou Tian-Tian; Xu Guo-Liang; Liu Lin*; Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation, iScience, 2020, 23(3): 0-100908. (Cell子刊, #共同一作)　
2. Huang Guian; Li Juan; Wang Hongning; Lan Xinyu; Wang Yajun*; Discovery of a Novel Functional Leptin Protein (LEP) in Zebra Finches: Evidence for the Existence of an Authentic Avian Leptin Gene Predominantly Expressed in the Brain and Pituitary, Endocrinology, 2014.9, 155(9): 3385-3396. (IF=4.5)
3. Huang Guian; He Chen; Meng Fengyan; Li Juan; Zhang Jiannan; Wang Yajun*; Glucagon-Like Peptide (GCGL) Is a Novel Potential TSH-Releasing Factor(TRF) in Chickens: I) Evidence for Its Potent and Specific Action onStimulating TSH mRNA Expression and Secretion in the Pituitary, Endocrinology,2014.11, 155(11): 4568-4580. (IF=4.5)
4. Huang Guian, Li J., Fu H., Yan Z., Bu G., He X., Wang Y. (2012). Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Domestic Animal Endocrinology, 43, 1-15 (IF=2.056)
5. Bu, Guixian#; Huang Guian#; Fu, Hao; Li, Juan; Huang, Simiao; Wang, Yajun. (2013) Characterization of the novel duplicated PRLR gene at the late-feathering K locus in Lohmann chickens. Journal of Molecular Endocrinology, 51, 261-276 (IF=3.621，#共同一作)
6. ) Identification of the receptors for somatostatin (SST) and cortistatin (CST) in chickens and investigation of the roles of cSST28, cSST14, and cCST2014; Gao, Shunyu; Li, Juan; Yan, Zhenxin; Wang, Yajun. (Huang GuianMeng, Fengyan; 14 in inhibiting cGHRH1–27NH2-induced growth hormone secretion in cultured chicken pituitary cells. Molecular and Cellular Endocrinology, 384: 83-95. (IF=4.241).
7. Wang, Yajun; Huang Guian; Li, Juan; Meng, Fengyan; He, Xiaping; Leung, Frederick C. (2012) Characterization of chicken secretin (SCT) and secretin receptor (SCTR) genes: A novel secretin-like peptide (SCT-LP) and secretin encoded in a single gene. Molecular and Cellular Endocrinology, 348: 270-280 (IF=4.192)
8. Wang, Yajun; Meng, Fengyan; Zhong, Yu; Huang Guian; Li, Juan. (2012) Discovery of a Novel Glucagon-like Peptide (GCGL) and Its Receptor (GCGLR) in Chickens: Evidence for the Existence of GCGL and GCGLR Genes in Nonmammalian Vertebrates. Endocrinology, 153, 5247-60 (IF=4.717).
9. Wang, Yajun; Wang, Crystal Ying; Wu, Yuting; Huang Guian; Li, Juan; *Leung, Frederick C. (2012) Identification of the Receptors for Prolactin-Releasing Peptide (PrRP) and Carassius RFamide Peptide (C-RFa) in Chickens. Endocrinology, 153: 1861-1874 (IF=4.717).